About the project

Malaria causes millions of deaths and poses significant economic challenges worldwide. There is an urgent need to improve malaria treatment by simplifying the administration of drugs and to make it more patient friendly to the malaria affected population, especially people in the poverty regions. The current proposal aims to develop a novel injectable 3D polymer scaffold with controlled dual-drug release to sustainably provide the therapeutic antimalarial drugs needed to treat acute malaria disease as well as to block the transmission of the malaria parasite to the vector mosquitoes. The device will be applied only once via simple intradermal injection and will release two different drugs, each one encapsulated in custom-made nanoparticle delivery system. This will enable a significant progress in the application of functional systems able to release concomitantly two drugs with different release profiles, making at the same time their uptake patient friendly and easily applicable.


Project partners

Leibniz-Institut für Polymerforschung Dresden e.V.
Sofia University
Stellenbosch University
University of Pretoria
University of the Witwatersrand
University of Leipzig Medical Center


More information could be find on the project website: https://www.polymerseparation.org/3d4d2-m-era-net/